Glycine Propionyl-L-Carnitine HCL (GPLC)
How does it work?
GPLC is a patented bonded form of propionyl-L-carnitine (PLC) bonded with the amino acid glycine.1 GPLC is used as a carnitine agent to increase nitric oxide levels which leads to vasodilation in vascular smooth muscle and can therefore assist in delivering oxygen and nutrients to muscular tissue more efficiently.2 Some studies have shown GPLC acts as an antioxidant and protects against lipid peroxidation as well as increasing nitric oxide levels simultaneously.3 GPLC is similar to the effects of PLC which assists the body to produce energy and increases circulation in vascular tissue hence its use in treating peripheral vascular disease , diabetes and erectile dysfunction.4
What results can be expected?
GPLC may assist in improving exercise performance and recovery through elevating nitric oxide levels through increasing vasodilation and blood flow to muscle tissue.5 GPLC also provides antioxidant activity against lipid peroxidation.6
1Glycine Propionyl-L-Carnitine and Nitric Oxide. (n.d.). Retrieved Feb 2014, from Bodybuilding: http://www.bodybuilding.com/fun/n_o_supplement_gplc.htm
2Bloomer, J et al. (2007). Glycine propionyl-L-carnitine increase plasma nitrate/nitrite in resistance trained men. J Int Soc of Sports Nutrition, 4(22). Retrieved Feb 2014, from http://link.springer.com/article/10.1186/1550-2783-4-22#page-1
3Bloomer, R et al. (2009). Glycine Propionyl-L-carnitine Modulates Lipid Peroxidation and Nitric Oxide in Human Subjects. International Journal for Vitamin and Nutrition Research, 79(3), 131. Retrieved Feb 2014, from http://medcontent.metapress.com/content/v20661q1q58797n1/
4WebMD. (2009). Vitamins and Supplements – Propionyl-L-Carnitine. Retrieved Jan 2014, from WebMD: http://www.webmd.com/vitamins-supplements/ingredientmono-803-PROPIONYL-L-CARNITINE.aspx?activeIngredientId=803&activeIngredientName=PROPIONYL-L-CARNITINE
6Bloomer, R et al. (2009). Glycine Propionyl-L-carnitine Modulates Lipid Peroxidation and Nitric Oxide in Human Subjects. International Journal for Vitamin and Nutrition Research, 79(3), 131. Retrieved Feb 2014, from http://medcontent.metapress.com/content/v20661q1q58797n1/