Acetyl L-Carnitine (ALC)
How does it work?
ALC, an acetylated ester form of L-Carnitine is involved in a myriad of biochemical processes such as improving normal healthy lipid and carbohydrate metabolism by assisting the delivery of fatty acids into mitochondria for the production of cellular energy.1 In the acetylated form of carnitine, ALC is able to cross the blood-brain barrier and support neuronal and mitochondrial health.2
What results can be expected?
Studies have shown that ALC reduced both physical and mental fatigue in elderly patients and improved cognitive status and physical funtions.3 ALC may also assist in treating Alzheimer’s disease, age-related memory loss, late-life depression, nerve pain4 and decreasing oxidative damage to the brain.5 Acetylcarnitine and Carnitine may help increase aerobic performance, anaerobic capacity and improve power output in athletes. It may also boost energy by assisting the body's burning of fats as fuel and enhances fat utilization during exercise.
By burning fat as fuel, the body's supply of glycogen stored in the liver is spared for heavier exertion, which helps increase stamina, endurance and energy supply.
Acetyl L-Carnitine may assist muscle function during and after exercise.
Assists with the conversion of body fat into energy.
L-Carnitine assists with the conversion of fatty acids.
Carnitine is essential for mitochondrial fatty acid oxidation, this is a primary fuel source for the heart and skeletal tissue.
1Braun, L. &. Cohen, M. (2010). Herbs and Natural Supplements (3rd ed.). Chatswood: Elsevier pp286-87.
2Braun, L. &. Cohen, M. (2010). Herbs and Natural Supplements (3rd ed.). Chatswood: Elsevier pp286-87.
3Malaguarnera, M. (2008). Acetyl L-carnitine (ALC) treatment in elderly patients with fatigue. Arch Gerontol Geriatr. , 46(2), 181-90. Retrieved Jan 2014, from http://www.ncbi.nlm.nih.gov/pubmed/17658628
4WebMD. (2009). Vitamins and Supplements - Acetyl L Carnitine. Retrieved Jan 2014, from WebMD: http://www.webmd.com/vitamins-supplements/ingredientmono-834-ACETYL-L-CARNITINE.aspx?activeIngredientId=834&activeIngredientName=ACETYL-L-CARNITINE
5Lui, J. (2004). Comparison of the effects of L-carnitine and acetyl-L-carnitine on carnitine levels, ambulatory activity, and oxidative stress biomarkers in the brain of old rats. Ann N Y Acad Sci., 1033, 117-131. Retrieved Jan 2014, from http://www.ncbi.nlm.nih.gov/pubmed/15591009